Described as “the world’s first hybrid anabolic/near hormonal product,” HGH Up is said to increase growth hormone production to unheard of levels.

The result? Manufacturers would like you to believe it’s “the most effective GH booster on the market.” But wouldn’t ever manufacturer and marketing company want you to believe that?

However, claims stuffed with pseudo-scientific jargon and unproven assertions never convince me and I hope they don’t convince others.

To get the real story on HGH Up, I did a little more research to find out what users can really expect.

Who Makes HGH Up?

HGH Up is manufactured and sold by Applied Nutriceuticals, a supplement company based in Charlotte, North Carolina.

According to the “About Us” section on AppNut.com, Applied Nutriceuticals has been around since 2006 and manufactures all their products in an in-house lab. The company currently sells 18 products through more than 30 online retailers and collects between $5,000 and $1 million in annual revenue [1].

However, Manta.com estimates the company’s employee count to be between 1 and 4, and the address given for company headquarters is in a small strip mall. This likely isn’t the large company you’d assume it is.

This isn’t necessarily a bad sign, but for a company that’s been in business for so long, I would have expected more growth over the years.

What Ingredients Are in HGH Up?

HGH Up contains vitamins, minerals, amino acids, and herbal extracts to increase growth hormone production. This is a diverse approach to increasing HGH levels, and one I haven’t seen often.

However, many of these ingredients are included in a 700 mg proprietary blend.

Generally, I don’t like proprietary blends because they disguise the exact amount of each ingredient in the product, instead listing the size of the blend itself. And, with 700 mg per serving, I’m not convinced Applied Nutriceuticals includes enough of each ingredient to be effective.
Nevertheless, let’s take a look at these ingredients.

Chlorophytum Borivilanium

This Indian herb is most often used to treat postpartum depression in women, but some say its ability to increase dopamine levels also leads to greater growth hormone production. In one Indian study, one chlorophytum borivilianum dose increased HGH production by 221% [1]. However these studies have not yet been replicated. What’s more likely is this extract improves sleep quality, which enhances HGH production.

Mucuna Pruriens

Better known as cow hage or velvet bean, mucuna pruriens works alongside chlorophytum borivilianum to boost HGH production and improve sleep quality [2]. Mucuna pruriens balances mood levelers to decrease anxiety and depression. Weight loss is a side effect, which improves body composition and muscle definition.

L-Carnitine L-Tartrate

L-carnitine is an amino acid that reduces fat mass, increases muscle, and boosts energy production [3]. L-carnitine l-tartrate provides these benefits, and also increases growth hormone production to increase exercise resistance and recovery [4].

Green Tea

Green tea has numerous health benefits, from preventing heart to disease to triggering weight loss. However, a recent study suggests the epigallocatechin gallate (GCG) in green tea also boosts growth hormone production. In this study, participants who took green tea for 90 days increased their HGH levels by more than 320%, which boosted IGF-1 levels by 24% [5].


Magnesium has long been used for increasing muscle mass and boosting energy production, but one study also suggests it may increase growth hormone [6]. However, this study involved cows. All evidence relating to magnesium and growth hormone in humans is anecdotal only, and related to magnesium’s beneficial effects on sleep.


Selenium is an amino acid and antioxidant linked to positive skin improvements, a benefit of HGH supplementation. It also increases growth hormone in a study involving female rats [7]. Studies involving humans are ongoing.

These ingredients may improve HGH production, through mainly by improving sleep levels. Some ingredients also mimic HGH benefits, which may give you the results you’re looking for.

However, because the proprietary blend prevents us from analyzing the formula further, we need to look at what past customers have to say.

What Do Customers Think?

HGH Up currently has an 8.3/10-star rating on Bodybuilding.com, a 6.9/10-star rating on SupplementReviews.com, and a 3.2/5-star rating on Ulta.com. These reviews tell me HGH Up is a solid product that performs a little better than average.

Individual customer reviews say HGH Up is good for fat loos, increased energy, and building muscle. Negative reviews focus on an expensive price, mild side effects, and a relatively ineffective formula.

Here are a few reviews that most represent customer sentiment toward HGH Up.

“I cannot honestly comment on the Test and HGH effects though. It’s virtually impossible to measure with such a small amount of boost. I have gotten gains, and I have vascularity I didn’t before. But I do not know if this product is having anything to do with it as I am a noob in the gym and I’m making all kindzzz of gains anyways.” –Gmosu22

“I did experience some strength gains while using this but the gains were ones that only i would notice..nothing earth shattering. One thing i really did notice is that my muscle density improved while using this. I wasnt overly impressed with the gains, but i did throw on around 3lbs.” –Dieatro14
“I lost some Bf and some weight while on this product but I can say that was from my diet, training, and other products that I was taking at the time. I will say the sleep I experienced while on this was great. ONCE I fell asleep I was out cold and experienced vivid and deep dreams. I did not notice any increase in libido. Noticed that my skin was looking better and healthier while taking this product. Furthermore I believe that this product is lacking in its proclaimed gh boosting abilities because the science behind the mucuna and Chlorophytum Borivilanium is not sound in my eyes and I did notice any out of the ordinary strength and muscle gains while on this product.” –AlphandOmega

As you can see, HGH Up provides some moderate benefits related to growth hormone, but most gains are largely thanks to a user’s diet and exercise program. HGH Up operates more as a helpful boost than an instigator.

Is HGH Up Expensive?

The suggested retail price for HGH Up is $69.99. With 150 capsules per bottle, this may seem like a great deal at first.

However, each serving size is 5 capsules, decreasing HGH Up’s lifespan to just a month—the standard lifespan for any supplement. When seen in this light, HGH Up is pretty expensive, considering the ingredients you get.

Fortunately, there are a few better deals to be had elsewhere online. The best purchasing options I found were:

Price: $38.95
Shipping: $5.95

Price: $39.99
Shipping: free

Price: $39.99
Shipping: $7.95

Price: $44.97
Shipping: $5.93

Sometimes Applied Nutriceuticals issues coupon codes through their Facebook and Twitter accounts, so be sure to follow them to get further savings on HGH Up.

Should You Try HGH Up?

It’s hard to go wrong with an HGH product. Generally, including a few target amino acids almost guarantees results. However, there are products that are merely effective, and then there are products that stand out from the crowd.

From what I’ve seen, HGH Up isn’t one of those. While its ingredients may help you improve your HGH levels, there’s nothing here you wouldn’t get with a less expensive incarnation of this product. Save your money for a product that really delivers instead.


[1] Manta.com. 2013. Applied Nutriceuticals. http://www.manta.com/c/mmsn1kf/applied-nutriceuticals.

[2] McCarthy, Cameron, Rick Alleman, Zach Bell, and Richard Bloomer. 2012. A dietary supplement containing chlorophytum borivilianum and velvet bean improves sleep quality in men and women. Integrative Medicin Insights: Vol. 7, 7-14.

[3] Goa, K.L and R.N. Brogden. 1987. L-carnitine. A preliminary review of its pharmacokinetics, and its therapeutic use in ischaemic cardiac disease and primary and secondary carnitine deficiencies in relationship to its role in fatty acid metabolism. Drugs: Vol. 34, Issue 1.

[4] Kraemer, W.J., J.S. Volek, D.N. French, M.R. Rubin, M.J. Sharman, Al Gomez, N.A. Ratamess, R.U. Newton, B. Jemiolo, B.W. Craig, and K. Hakkinen. 2003. Journal of Strength and Conditioning Research: Vol. 17, Issue 3.

[5] Di Pierro, F., et al. 2009. Alternative Medicine Review: Vol. 14, Issue 2.

[6] Emery, R.S., J. Luoma, J. Liesman, J.W. Thomas, H.A. Tucker, and L.T. Chapin. 1986. Effect of serum magnesium and feed intake on serum growth hormone concentrations. Journal of Dairy Science: Vol. 69, Issue 4.

[7] Ewan, R.C. 1976. Effect of selenium on rat growth, growth hormone and diet utilization. Journal of Nutrition: Vol. 106, Issue 5.

Doug Says:

This product will work but u must up the dose take 5 b4 bed and 5 when you wake up with it and my stack I put 50lbs on my bench within 2 months 300 max to 350 max and I experienced no negative side effects. To me it’s a great product.

May 4, 2014 at 7:26 pm

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